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About 8 results for "HCL Me G1"

Analysis of Host Gene Expression Profile in HIV-1 and HIV-2 In...

Krishnakumar Devadas, Santanu Biswas, Mohan Haleyurgirisetty, Owen Wood, Viswanath Ragupathy, Sherwin Lee, Indira Hewlett x DOI: 10.1371/journal.pone.0147421 Figures Abstract HIV replication is closely regulated by a complex ... Plosone.org, 1 week ago

Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6

Abstract The DNA polymerase and ribonuclease H (RNase H) activities of human immunodeficiency virus type 1 (HIV-1) are needed for the replication of the viral genome and are validated drug targets. However, there are no approved drugs inhibiting ...
 Plosone.org2 weeks ago

Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity

Introduction Precisely regulated cell-cell adhesion is crucial for the development and functioning of multicellular organisms ( Nelson, 2008 ). In vascular endothelial cells (EC), cell-cell contacts formed by adherens and tight junctions ( Bazzoni, ...
 Elifesciences2 weeks ago

Functionalized Mesoporous Silica via an Aminosilane Surfactant Ion Exchange Reaction: Controlled Scaffold Design and Nitric Oxide Release

Introduction Nitric oxide (NO), an endogenous diatomic free radical, mediates multiple physiological processes, including angiogenesis, (1) blood pressure regulation, (2) wound healing, (3, 4) and the immune response. (5, 6) In vivo, nitric oxide ...
 ACS Applied Materials & Interfaces3 weeks ago

Nmnat3 Is Dispensable in Mitochondrial NAD Level Maintenance In Vivo

Abstract Nicotinamide adenine dinucleotide (NAD) is an essential co-enzyme mediating various enzymatic reactions. Mitochondrial NAD particularly occupies a considerable amount of total NAD in cells, and serves as a co-enzyme in tricarboxylic acid ...
 Plosone.org3 weeks ago

Oligogalacturonic acids promote tomato fruit ripening through the regulation of 1-aminocyclopropane-1-carboxylic acid sy

Research articleBMC Plant Biology201616:13DOI: 10.1186/s12870-015-0634-y Ma et al.2016Received: 28May2015Accepted: 30September2015Oligogalacturonic acids (OGs) are oligomers of alpha-1,4-linked galacturonosyl residues that are released from cell ...
 MyInforms4 weeks ago

Hydrogen Evolution from Water under Aerobic Conditions Catalyzed by a Cobalt ATCUN Metallopeptide

Hydrogen is touted as an energy-dense carbon-free fuel; however, most hydrogen is currently produced via steam reforming of hydrocarbons. (1) A potentially more sustainable route to producing hydrogen is the reduction of aqueous protons. Hydrogenase ...
 Inorganic Chemistry1 month ago

2-Benzazolyl-4-Piperazin-1-Ylsulfonylbenzenecarbohydroxamic Acids as Novel Selective Histone Deacetylase-6 Inhibitors with Antiproliferative Activity

Introduction Aberrant regulation of gene expression is at the basis of several human diseases including many forms of cancer. This is partly the result of deregulation of DNA methylation or the post translational modification of histone tails.
 Plosone.org1 month ago
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