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About 8 results for "HCL Me G1"

A Membrane-Type-1 Matrix Metalloproteinase (MT1-MMP) Discoidi...

Introduction Cells in multicellular organisms are surrounded by a complex three-dimensional (3D) macromolecular extracellular matrix (ECM). This matrix, traditionally thought to serve a structural function providing support and strength to cells ... Plosone.org, 1 week ago

Evaluation of the Synuclein-γ (SNCG) Gene as a PPARγ Target in Murine Adipocytes, Dorsal Root Ganglia Somatosensory Neurons, and Human Adipose Tissue

Abstract Recent evidence in adipocytes points to a role for synuclein-γ in metabolism and lipid droplet dynamics, but interestingly this factor is also robustly expressed in peripheral neurons. Specific regulation of the synuclein-γ gene ( Sncg ) ...
 Plosone.org2 weeks ago

Peptide for determining actin structures in living cells

The present invention relates to novel peptides capable of binding to action. The peptides are useful in methods for detecting actin in vitro or in living cells. Description of the Invention BACKGROUND OF INVENTION Actin is involved in many ...
 PharmCast3 weeks ago

S100A9 Induced Inflammatory Responses Are Mediated by Distinct Damage Associated Molecular Patterns (DAMP) Receptors In Vitro and In Vivo

Abstract Release of endogenous damage associated molecular patterns (DAMPs), including members of the S100 family, are associated with infection, cellular stress, tissue damage and cancer. The extracellular functions of this family of calcium ...
 Plosone.org1 month ago

A Click Approach to Novel D-Ring-Substituted 16α-Triazolylestrone Derivatives and Characterization of Their Antiproliferative Properties

Introduction Since cancerous disorders are the second leading cause of death worldwide, following cardiovascular diseases, improvement of their treatment is currently one of the greatest challenges. A survey of epidemiological data from 184 ...
 Plosone.org1 month ago

A Lipoxygenase from Red Alga Pyropia haitanensis, a Unique Enzyme Catalyzing the Free Radical Reactions of Polyunsaturated Fatty Acids with Triple Ethylenic Bonds

Introduction Compounds derived from the oxidative metabolism of polyunsaturated fatty acids (PUFAs) are found in terrestrial plants, marine algae and animals, serving as an intrinsic response to external stimuli [ 1 ]. Products synthesized via such ...
 Plosone.org1 month ago

N-Terminal and C-Terminal Domains of Calmodulin Mediate FADD and TRADD Interaction

Abstract FADD (Fasassociated death domain) and TRADD (Tumor Necrosis Factor Receptor 1-associated death domain) proteins are important regulators of cell fate in mammalian cells. They are both involved in death receptors mediated signaling pathways ...
 Plosone.org1 month ago

Creating Novel Activated Factor XI Inhibitors through Fragment Based Lead Generation and Structure Aided Drug Design

Introduction A well balanced haemostasis system is important to both minimize blood loss and disturbances of blood flow. Upon injury of the vessel wall, blood is exposed to tissue factor which via a cascade reaction leads to thrombin generation and ...
 Plosone.org1 month ago
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