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About 31 results for "Mk 5172"

Structural and Thermodynamic Effects of Macrocyclization in HC...

Recent advances in direct-acting antivirals against Hepatitis C Virus (HCV) have led to the development of potent inhibitors, including MK-5172, that target the viral NS3/4A protease with relatively low susceptibility to resistance. MK-5172 has a ... ACS Chemical Biology, 1 month ago

Thomson Reuters spotlights the R&D trends behind 2016's top blockbusters

Last year Thomson Reuters started 2015 by pegging 11 likely blockbusters in the late-stage pipeline. This year, that number has shrunk to 7, as rare diseases and new drug cocktails continue to grab the attention of the most ambitious players in the ...
 FierceBiotech6 days ago
Pharmafile

Revealed: analysts predict seven highest-earning pharma blockbusters

Seven drugs are predicted to earn annual sales of more than $1 billion a year by 2020 Seven new drugs currently in development will enter the market this year and earn sales of more than $1 billion a year by 2020, analysts predict. According ...
 Pharmafile6 days ago New Drugs from Abbvie, Gilead, Intercept and Merck Forecast to Achieve Blockbuster Status by 2020  BioSpace1 week ago
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Grazoprevir appears safe for HCV genotype 1

Grazoprevir dosed at 100 mg was safe and effective among adults for the treatment of hepatitis C virus infection, according to study data published in the Journal of Viral Hepatitis . In a dose-ranging clinical trial conducted across the UK, ...
 Orthopedics Today2 weeks ago
JPMA

Squamous cell carcinoma of oral tongue in young patients - A 10 years tertiary care experience

Shakeel Uz Zaman, Anwar Suhail ( Section of ENT, Aga Khan University Hospital, Karachi. ) Mohammad Adeel ( Department of Otolaryngology, Head & Neck Surgery, Aga Khan University Hospital, Karachi. ) Abstract Objective: To evaluate the ...
 JPMA3 weeks ago

HCV Highlights: HepDart/AASLD - Current HCV Treatments - New HCV Treatments in Development

New HCV Treatments in Development Sofosbuvir/Ledipasvir Sofosbuvir/GS5816 (Velpatasvir) Elbasvir/Grazoprevir Abbvie 3D ABT493+ABT530 MK3682/MK8408+Grazoprevir Sofosbuvir/GS5816+GS9857 Ledipasvir+Sofosbuvir+Vedroprevir 8 weeks ...
 National AIDS Treatment Advocacy Project3 weeks ago

Looking Back, Looking Ahead at Treatment Developments

Since early in 2015, this has been a very eventful year for hepatitis C therapeutics and we can summarize our experiences over the last year much like Clint Eastwood's spaghetti Western: The Good, The Bad and The Ugly . The Good The good is ...
 Orthopedics Today3 weeks ago

Merck at AASLD / HepDart 2015

AASLD: Summary from AASLD 2015 for Hepatitis C Beyond 95% SVR cure rates: still room for improvement? Jurgen K. Rockstroh M.D., Professor of Medicine University of Bonn, Germany ------------------------- Merck Announces U.S. Food and Drug ...
 National AIDS Treatment Advocacy Project3 weeks ago Summary from AASLD 2015 for Hepatitis C Beyond 95% SVR cure rates: still room for improvement?  National AIDS Treatment Advocacy Project1 month ago
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