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About 801 results for "tyrosine"

PHLPP suppresses receptor tyrosine kinase levels [Biochemistry]

Gloria Reyes a , 1 , Matt Niederst a , b , 1 , Ksenya Cohen-Katsenelson a , Joshua D. Stender c , Maya T. Kunkel a , Muhan Chen d , John Brognard a , 2 , Emma Sierecki a , 3 , Tianyan Gao e , Dawid G. Nowak c , Lloyd C. Trotman d , ... PNAS, 1 week ago

8 images for tyrosine

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Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance - Abstract

Activation of EGFR signaling pathway leads to prostate cancer bone metastasis; however, therapies targeting EGFR have demonstrated limited effectiveness and led to drug resistance. miR-203 levels are down-regulated in clinical samples of primary ...
 UroToday1 week ago Cabozantinib Bombs in Prostate Cancer  Medscape2 weeks ago

Genomic analysis reveals that high-risk leukemia subtype becomes more common with age

The stage has been set to determine if drugs called tyrosine kinase inhibitors will extend the lives of patients with the high-risk acute lymphoblastic leukemia subtype, researchers report.
 Big News Network6 days ago Genomic Analysis Reveals that a High-Risk Leukemia Subtype Becomes More Common with Age  PRWeb1 week ago Gene-sequencing leukemia research could boost Dx and treatment for kids with a rare disease subtype  Fierce BioMarkers2 days ago St. Jude Children's Research Hospital Release: Genomic Analysis Reveals That A High-Risk Leukemia Subtype Becomes More Common With Age  BioSpace1 week ago

Kolltan to float on Nasdaq

Kolltan Pharmaceuticals, a seven-year-old US developer of drugs targeting receptor tyrosine kinase (RTKs), is opening up its equity base to outside investors in order to advance its lead preclinical programmes. The Connecticut-based cancer company, ...
 M&A Portal3 days ago Kolltan Pharmaceuticals Files for Its Initial Public Offering  Dow Jones Financial Information Services6 days ago Kolltan Cancer Study Results for KTN3379, Targeting ErbB3, Support Evaluating Combinations with Targeted Therapies  4 Traders3 days ago Kolltan Presents Results for KTN3379, Targeting ErbB3, Support Evaluating Combinations with Targeted Therapies  Individual.com20 hours ago

Data on Cancer Gene Therapy Reported by Researchers at Chang Gung Memorial Hospital [A dual tyrosine kinase inhibitor lapatinib suppresses...

 HispanicBusiness.com1 day ago Findings from Queen Mary University Provide New Insights into Cancer Gene Therapy (The receptor tyrosine kinase Axl regulates cell-cell adhesion and...  HispanicBusiness.com1 week ago REGENERON PHARMACEUTICALS : Patent Application Titled "Readily Isolated Bispecific Antibodies with Native Immunoglobulin Format" Published Online  4 Traders1 day ago Patent Application Titled "Anti-Erbb3 Antibodies in Combination with Paclitaxel for Treatment of Gynecological Cancers" Published Online  4 Traders1 day ago

New Arteriogenesis Study Findings Have Been Reported by Researchers at Merck Serono SA (Inhibition of protein tyrosine phosphatases enhances cerebral...

New Arteriogenesis Study Findings Have Been Reported by Researchers at Merck Serono SA (Inhibition of protein tyrosine phosphatases enhances cerebral collateral growth in rats) (Inhibition of protein tyrosine phosphatases enhances cerebral ...) ...
 4 Traders1 day ago

Why do mushrooms turn brown

The crystal structure of latent PPO4 mushroom tyrosinase is converted via proteolytic removal of the C-terminal domain resulting in the active form of tyrosinase. As a result of this reaction, the type-3 copper center becomes exposed to monophenolic ...
 AgroTimes.com2 days ago Why Do Mushrooms Turn Brown?  Scicasts1 week ago Why do mushrooms turn brown? Chemists explore the mechanisms behind food spoilage  PhysOrg.com1 week ago Chemists Examine Enzyme Responsible for Food Browning  Laboratory Equipment1 week ago

Effects of fostamatinib, an oral spleen tyrosine kinase inhibitor, in rheumatoid arthritis patients with an inadequate response to methotrexate: Results from a phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study

Abstract Objective. This phase III, 52-week study (NCT01197521; OSKIRA-1) compared fostamatinib and placebo (for 24 weeks) in patients with active rheumatoid arthritis and an inadequate response to methotrexate (MTX) therapy. Methods. Patients ...
 Arthritis & Rheumatism3 days ago

Antitumor Effect of the Tyrosine Kinase Inhibitor Nilotinib on Gastrointestinal Stromal Tumor (GIST) and Imatinib-Resistant GIST Cells

by Hiroyuki Sako, Kazumasa Fukuda, Yoshiro Saikawa, Rieko Nakamura, Tsunehiro Takahashi, Norihito Wada, Hirohumi Kawakubo, Hiroya Takeuchi, Tai Ohmori, Yuko Kitagawa Despite the benefits of imatinib for treating gastrointestinal stromal tumors ...
 Plosone.org3 days ago The tyrosine kinase inhibitor nilotinib has antineoplastic activity in prostate cancer cells but up-regulates the ERK survival signal-Implications for targeted therapies - Abstract  UroToday1 week ago

In vitro effect of IL-2 in combination with pazopanib or sunitinib on lymphocytes function and apoptosis of RCC cells - Abstract

OBJECTIVE: Combination of immunotherapy with tyrosine kinase inhibitors (TKIs) has been used with some success for the treatment of metastatic renal cell carcinoma. Herein we evaluate the in vitro effect of high-dose interleukin-2 (HDIL-2) and ...
 UroToday1 week ago
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