This is a summary of the European public assessment report (EPAR) for Lamivudine/Zidovudine Teva. It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the medicine to reach its opinion in favour of granting a marketing ... European Medicines Agency, 1 month ago
Silibinin mitigates zidovudine-induced hepatocellular degenerative changes, oxidative stress and hyperlipidaemia in rats
R Raghu B Jesudas G Bhavani D Ezhilarasan S Karthikeyan ⇑ Food and Hepatotoxicology Laboratory, Department of Pharmacology and Environmental Toxicology, Dr. A.L.M. Post Graduate Institute of Basic Medical Sciences, ...Human And Experimental Toxicology, 2 weeks ago
Drug Name(s) RETROVIR FDA Application No. (NDA) 019655 Active Ingredient(s) ZIDOVUDINE Company VIIV HLTHCARE Original Approval or Tentative Approval Date March 19, 1987 Chemical Type ...U.S. Food and Drug Administration, 4 weeks ago
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Disclosed herein are cell penetrating peptides useful as treatment for Human Immunodeficiency Virus. Description of the Invention FIELD OF THE INVENTION Disclosed herein are cell penetrating peptides useful as therapeutics for Human ...PharmCast, 36 minutes ago
Could antiretroviral neurotoxicity play a role in the pathogenesis of cognitive impairment in treated HIV disease?
"This area is likely to become of increasing interest over the coming years, given that the cohort of PLWH is ageing, leading to an increase in comorbidity and drug-drug interactions with the added complication of age-related changes in the ...National AIDS Treatment Advocacy Project, 5 days ago
Abstract Cardiovascular disease (CVD) is the leading cause of mortality worldwide. Moreover, sex and age are considered major risk factors in the development of CVDs. Mitochondria are vital for normal cardiac function, and regulation of ...Plosone.org, 5 days ago
A dosage form exhibiting delayed transit time through the GI tract. The dosage form comprises a plurality of buoyant particles, each comprising an inner drug-containing core, an intermediate layer surrounding said core and a release rate-controlling ...PharmCast, 1 week ago
What Is Needed? Marc Bulterys, Robert J. Berry, D. Heather Watts Disclosures AIDS.2014;28(18):2777-2780. Prevention of maternal-to-child transmission (MTCT) of HIV remains a priority, as globally, approximately 700 infants are newly infected ...General Medicine eJournal, 1 week ago
Krekels EH, Danhof M, Tibboel D, et al . Ontogeny of hepatic glucuronidation; methods and results. Curr Drug Metab 2012;13:72843. Ince I, Knibbe CAJ, Danhof M, et al . Developmental changes in the expression and function of Cytochrome P450 3A ...General Medicine eJournal, 2 weeks ago
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